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The Dinner Group

Current Group Members

Principal Investigator

Secretary

Postdoctoral Scholars

Graduate Students

Undergraduate Students

Dinner Group Alumni

Contact Information

All offices are in the
Gordon Center for Integrative Science (GCIS)
929 East 57th Street
Chicago, Illinois 60637
Lab Phone: 773-702-7232

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Principal Investigator

Aaron Dinner
Office: GCIS E139E
Phone: 773-702-2330
Fax: 773-702-4180
E-mail:







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Secretary

Zena Anderson
Office: GCIS E145
Phone: 773-702-7180
E-mail:


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Postdoctoral Scholars

Shiladitya Banerjee
Postdoctoral scholar with the group since 2013
Office: GCIS E208
E-mail:
Education
2013: Ph.D. in Physics (Advisor: Christina Marchetti), Syracuse University
2008: Bsc., Chennai Mathematical Institute.
Research

My research focuses on developing theoretical models for understanding collective behavior in active matter systems. Of particular interest is the actomyosin cytoskeleton, which is the site for mechanical force generation in living cells. To investigate the origin of these cellular forces, I'm currently developing microscopic models for motor-filament interactions in the cytoskeletal gel. A key challenge is to delineate the cellular mechanical response by modeling its inherent stochasticity and non-thermal activity. The goal is to qualitatively and quantitatively capture the emergent spatiotemporal patterns and nonequilibrium dynamics observed in vitro and in vivo experiments. To this end, I'm working closely with the experimental groups of Margaret Gardel and Norbert Scherer. A successful microscopic description can throw significant light on how to control cellular dynamics by specific design of biochemical components.

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Srividya Iyer-Biswas
Postdoctoral scholar with the group since 2011
Office: GCIS E135
E-mail:
Education
2009: Ph.D. in Physics, Ohio State University
Research

I work on understanding the physical principles governing stochastic single cell behavior, evidenced in three different contexts: cell-to-cell variability in copy numbers, the timing of key events, and the spatial locations of key geometrical features. Theoretically, I develop non-traditional analytical approaches for doing this, from a top-down perspective, that do not make ad hoc assumptions, such as, the noise must be delta-correlated white noise, that the networks must be quasi-linear, the system must be in steady state, etc. Experimentally, I have helped develop a unique combination of technologies that allows observing single cells grow and divide for >100 generations, under invariant environmental conditions, with enough precision to elucidate the scaling laws governing fluctuations in growth and division at the single-cell level. I am also interested in the overarching systems design question of how cells must compute and optimize the energetic costs of efficient information transduction. Please see my personal website at http://home.uchicago.edu/~iyerbiswas/.


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Seyit Kale
Postdoctoral scholar with the group since 2012
Office: GCIS E126
E-mail:
Education
2012: Ph.D. in Biohysics and Structural Biology (Advisor: Judith Herzfeld), Brandeis University
Research

My research focuses on enhanced sampling methods for studying rare events in chemistry. Typical timescales we can access with molecular calculations are orders of magnitude smaller than those associated with most biological phenomena. Demand for more accurate, higher levels of theory exacerbates this gap. To circumvent this issue, we develop novel computational methods that enforce a more homogeneous statistical sampling than suggested by natural thermodynamic distribution. In collaboration with Prof. Jonathan Weare, I work on new approaches for how we can accelerate reaction path search and optimization problems typically encountered in chemistry and biochemistry.


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Graduate Students

Herman Gudjonson
Graduate Student with the group since 2013
Office: GCIS E126
E-mail:
Education
2012: A.B., Harvard University
Research

Single-cell genome analysis for understanding egulatory networks in innate lymphoid cell (ILC) development.


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Alan Hutchison
Graduate Student with the group since 2012
Office: GCIS E135
E-mail:
Education
2011: B.S., Yale University
Research

Genome-wide rhythm detection, regulatory network assembly, theoretical ecology.


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Monika Scholz
Graduate Student with the group since 2013
Office: GCIS E135
E-mail:
Education
2012: Dipl.Phys, TU Dresden
2010: B.Sc. in Physics, University of Wurzburg
Research

Stochastic processes.


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Eugene Leypunskiy
Graduate Student with the group since 2013
Office: KCBD
E-mail:
Education
2011: B.A., Princeton University
Research

Fitness in circadian systems.


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Jeremy Tempkin
Graduate Student with the group since 2013
Office: GCIS E126
E-mail:
Education
2012: B.S., University of Puget Sound
Research

Rare event simulations.


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Erik Thiede
Graduate Student with the group since 2014
Office: GCIS E126
E-mail:
Education
2013: B.S., University of North Carolina
Research

Theory and practice of rare event algorithms.


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Undergraduate Students

Ruby An
Undergraduate Student with the group since 2014
Office: GCIS E126
E-mail:
Research

Bioinformatics of circadian rhythms.


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